ISSN NO:2394-2401 (Online)

ISSN NO:2394-384X (Print)

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CALL FOR PAPERS      SUBMISSION LAST DATE   31th January, 2019 FOR FEBRUARY ISSUE      

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International Journal of Sciences and Applied Research (IJSAR) is a peer reviewed, open access International Scientific Journal dedicated for rapid publication of high quality original research articles as well as review articles in major areas of basic and applied sciences. International Journal of Sciences and Applied Research is published monthly. IJSAR with an internationally recognized editorial board emphasizes on producing high quality research content in a timely manner.

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Tittle : Studies on bioactive prodigiosin of serratia marcescens isolated from natural sources

Author(s) : Hariyali H. Sorathiya and Manisha N. Shah*

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Abstract:

Prodigiosin is a natural red colored pigment that specifically found to produced by many strains of Serratia marcescens and other related organisms as a secondary metabolites. Prodigiosin has a wide variety of biological activities and hence its efficacy optima strive researcher. Our present study aimed to determine antimicrobial, antifungal and antibiofouling activities of prodigiosin produced by Serratia marcescens isolated from various natural sources. Among the red pigment producing isolates, S8 isolate a higher pigment producer, was selected for further studies (was identified as Serratia marcescens by 16S rRNA sequencing, NCBI Accession No. MH145360). From 16S rRNA analysis, phylogenetic tree was constructed to study its phylogenic relationship. Antimicrobial activity of pigment showed reveals its effectiveness against gram positive organisms. Prodigiosin showed antifungal activity against Aspergillus niger, Mucor hiemalis, Fusarium enumartii and Rhizopus stolonifer. Prodigiosin was also known to reduce the adhesion of biofouling organisms such as Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus, hence can be used as antibiofoulant.

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