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International Journal of Sciences and Applied Research (IJSAR) is a peer reviewed, open access International Scientific Journal dedicated for rapid publication of high quality original research articles as well as review articles in major areas of basic and applied sciences. International Journal of Sciences and Applied Research is published monthly. IJSAR with an internationally recognized editorial board emphasizes on producing high quality research content in a timely manner.

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Tittle : Analysis of the antibacterial and thrombolytic activity of the methanolic extract of citrus sinensis peel

Author(s) : Najneen Ahmed, Mantasha Tabassum, Sharmin Ahmed, Shagufta Jasmin Subi, Mst Marium Begum

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Abstract:

Abstract 

Citrus sinensis (C. sinensis), a member of the Rutaceae (citrus family) has been traditionally used for various ailments such as asthma, hypertension, microbial infections, diabetes, tuberculosis, etc. It is rich in many phytochemicals which include flavonoids, saponins, tannins, glycosides, limonene, citral, neohesperidin, naringin, rutin, rhamnose, eriocitrin, and vitamin C. In this study the antibacterial activity of the methanolic extract of C. sinensis was investigated on some bacterial strains like Pseudomonas aeruginosa, Bacillus cereus and Klebsiella sp that are responsible for gastrointestinal disorder. The different concentrations (5 mg/mL, 10 mg/mL, 15 mg/mL, 20mg/mL and 25 mg/mL) of the sample have been used to evaluate the antimicrobial activity and increment in the antimicrobial activity was found with the increasing concentration of the sample. In the investigation of the thrombolytic activity of the C. sinensis methanolic peel extract, weak thrombolytic activity (26%) was found.

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